HEALTH

Gene Silencing Benefit of Zodasiran in Hyperlipidemia

LYON, France — The drug zodasiran (formerly ARO-ANG3), which targets the production of a liver protein, substantially lowers triglyceride and a range of lipoprotein levels in patients with mixed hyperlipidemia who are stable on optimal statin therapy, according to ARCHES-2 study investigators. The hepatocyte-targeted small interfering (si) RNA was designed to silence the expression of …

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